Institute of Health Promotion and Rebirth  of  People of Ukraine
A.Potopalsky Charity Fund
Institute of Molecular Biology and Genetics
ukr rus
eng





International scientific-practical forum
"BASES OF MOLECULAR-GENETIC HEALTH IMPROVEMENT OF BOTH HUMAN AND ENVIRONMENT"
31 May - 1 June 2005

The materials newly present the results of the formation and development of a new scientific direction of molecular-genetic improvement of human health and the environmental protection, which are especially relevant at any time
of environmental and man-made disasters.

Organizer: National Academy of Sciences of Ukraine, Institute of Molecular Biology and Genetics of NAS of Ukraine, Institute of Health Promotion and Rebirth of People of Ukraine, Charitable fund of A.Potopalsky "Healer given by heaven"

Sponsors: Scientific Production Centre Closed Joint-Stock Company “Borschagovsky Chemical Pharmaceutical Plant”, Kyiv; Closed Joint-Stock Company “Medherbs”, Zhitomir; Scientific Production Ltd. “Ecomed”, Kyiv


Forum Materials:

1. The role of natural biologically active substances, their analogues and modification products in a human and environmental molecular-genetic sanitation.

1.1. The role of Amitozyn, antitumoral and immunomodulatory preparation, in the tumor growth correction system.

Potopalsky A.I., Kyiv
Phytochemical antitumor preparation amitozyn with antiviral and immunomodulating action marks the beginning of a new scientific direction of health promotion and environment enhancement on the molecular level
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Dronov O.I., Susak Ya.M., Kryuchina E.A., Kyiv
Combined therapy of patients with pancreatic cancer complicated with jaundice using amitozyn preparation
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Dronov O.I., Susak Ya.M., Tsymbalyuk R.S., Kyiv
Case of treatment of hepatocellular adenocarcinoma
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Dronov O.I., Susak Ya.M., Deneka E.R., Kyiv
Therapeutic pathomorphism of pancreas cancer under the effect of amitozyn preparation
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Susak Ya.M., Gaponov V.V., Zemskov S.V., Procopchuk O.L., Lubynets T.V., Kyiv, Ulm (Germany)
Case of treatment of the skin melanoma with rectum metastasis using celandine preparations
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Susak Ya.M., Dronov O.I., Osinsky S.P., Potopalska Yu. A., Potopalsky A.I., Kyiv
Study of anticancer and modificating activity of amitozyn complex application
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Kovalchuk V.M., Gulya B.M., Berdichevska N.R., Potopalsky A.I., Kyiv, Zhitomir (Ukraine)
Afterhistory of the oncological patients treatment using amitozyn preparation
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Procopchuk O.L., Ulm (Germany)
New modalities of greater celandine preparations (ukrain, amitozyn) application for complex treatment of cancer
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1.2. Molecular-genetic mechanisms of Amitozyn effect, substantiation of the perspective courses of its complex use and other courses of these researches.

Sapozhnikov A.I., Svirshchevskaya E.V., Zaika L.A., Bolsunova O.I., Potopalskaya Yu.A., Potopalsky A.I., Kishinec R., Reshetov P.D., Moscow, Kyiv
Amitozyn – an immunity regulator
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Grinevich Yu.A., Martinenko S.V., Hranovskaya N.N., Bendyug G.D., Kyiv
Influence of amitozyn preparation on antitumor resistance and immune system of the organism
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Shvachko L.P., Bukh I.G., Alekseeva I.V., Potopalsky A.I., Kyiv
Molecular characteristics of amitozyn antitumor action
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Shestakova T.S., Porubleva L.V., Palchikovska L.G., Potopalsky A.I., Kyiv
Influence of amitozyn and some celandine alkaloids on transcription in vitro
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Yashuk V.M., Dudko O.V., Kruglova E.B., Yermak E.L., Kornelyuk O.I., Kordysh M.O., Voloshyuk T.P., Potopalska Yu.A., Potopalsky A.I., Zaika L.A., Bolsunova O.I., Terentyev A.G., Kyiv, Kharkiv
Spectral researches of amitozyn-nucleic ACIDS interaction
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Yashchuk V.M. Dudko O.V., Zayika L.A., Bolsunova O.I., Potopalska J.A., Potopalsky A.I.
The Luminescent Manifestation of the DNA – Amitozine’s Alkaloid Interaction
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Zavelevich M.P., Philchenkov O.O., Hranovska N.M., Osip Yu.L., Kaminsky V.O., Lucik M.D., Stoyka R.S., Kyiv
Influence of chelidonin, cheliritrin, and sanguinarin on the cellular cycle of lymphoblastic human leukemia MT-4 line: comparative analysis of their DNA-recognizing capability
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Philchenkov A.A., Zavelevich M.P., Hranovskaya N.N., Zaika L.A., Potopalsky A.I., Kyiv
Activation of kaspaze-3 under amitozyn effect on the cells of lymphatic human leukemia MT-4 line
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Potopalskaya Yu. A., Lukash L.L., Pidpala O.V., Kyiv
Study of the amitozyn effect on the cells of ovary teratoblastoma of human (RA-1 line cells)
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Abrahamovich E. (O.)S., Abrahamovich O.O., Potopalsky A.I., Abrahamovich L.E., Abrahamovich Ya.E., Lviv
Perspectives of treatment the systemic diseases of connective tissue with amitozyn
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Yurkevich L.N., Potopalskaya Yu.A., Negrebetskaya Ye. M., Kyiv
Inhibition of plant tumors growth with antitumor preparation amitozyn and its analog amitozynoberamid
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Voloshchuk T.P., Patskovsky Yu.V., Potopalsky A.I., Kyiv
The obtaining of antitumor preparations from alkylated nucleic acids and their monomeric components
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Kruglova E.B., Ermak E.L., Voloshchuk T.P., Potopalskaya Yu.A., Potopalsky A.I., Kharkov, Kyiv
Investigation of amitozyn1, modified by triethylenethiophosphoramide of chelidonium majus alkaloids, and thymus DNA interaction at the presence of stained biologically active markers
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1.3. Antiviral, immunomodulatory and antitumoral preparation - Izatizon and its analogues.

Loziyk L.V., Potopalsky A.I., Mirolyibova A.N., Bessarabov B.F., Lviv, Kyiv, Moscow
Overall Results and Prospects of 35-year izatizon studying
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Lozyuk L.V., Potopalskiy A.I., Shariy T.I., Lviv, Kyiv
Izatizon application in the veterinary medicine
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Bolsunova O.I., Potyagaylo A.L., Govorun D.M., Zaika L.A., Kharchenko V.M., Kyiv
Immuno-biological activity of izatizon and its connection with structurally conformational properties of the metisazone molecule
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Bolsunova O.I., Patsckovskiy Y.V., Rubalko S.L., Zayika L.A., Potopalsky A.I., Kyiv
Activity of izatizon concerning adenoviral infection in vitro
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Bolsunova O.I., Kyiv
Functional conditions of donors lymphocytes under the influence of the antiviral preparation izatizon
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Gavrilyuk S.M., Mikheeva I.V., Thir G.A., Hutor I.L., Pechkovsky K.E., Kyiv
High izatizon efficacy in stomatology
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Muzyka O.F., Kyiv
Izatizon application experience in the polyclinics
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Zhyrun Y.V., Miroshkin V.O., Zhyrun V.N., Feldman M.Y., Ostapovich Y.M., Stryy (Ukraine)
Experience of Izatizon application for male uresis system treatment under viral and inflammatory diseases
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Kotsur Y.I., Stryy (Ukraine)
Comparative analysis results of izatizon application during the outpatient treatment of eye viral diseases
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Pogurskyi G.I., Pidoprygora G.I., Bereza V.I., Potopalskiy A.I., Kyiv
Therapeutic effectiveness of izatizon application in veterinary
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Lozyuk L.V., Onischuk P.D., Potopalskiy A.I., Lozyuk R.M., Sokolskiy S.S., Melnik V.N., Lviv, Kyiv, Krasnodar
Izatizon application, its analogs and new medicinal forms for bee rehabilitation
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Bryk I., Stryy (Ukraine)
Izatizon application experience for bee rescue from fungal and viral diseases
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Pudyak V.O., Sydor I.Y., Stryy (Ukraine)
Izatizon application for bee treatment and prevention from viral and fungal diseases
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Drozda V., Kyiv
Operative breeding and utilization technology of the synovigene entomophages – composing part of the plant protection integrated systems
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Drozda V., Potopalsky A., Kyiv
Characteristics of the exogenous nucleic acids application in the technology of silkmoth Antheraea pernyi G.-M. growing
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Potopalsky A., Drozda V., Kyiv
Technological characteristics of the exogenous nucleic acids application in the Bombyx mori L. growing
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Cilyurik A., Drozda V., Potopalsky A., Kyiv
Experimental vindication of the optimal regimens of the exogenous nucleic acids use in the silkmoth Antheraea pernyi G.M. growing
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Shevchenko T., Drozda V., Potopalsky A., Kyiv
Physiological mechanisms and specificity of silkmoth Bombyx mori L. response on exogenous nucleic acids effects
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Steshenko O.V., Kyiv
Effect of Izatizon on the plant productivity
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2. Modern molecular-genetic aspects of human and environmental sanitation.

2.1. Establishment of new antiviral, antimicrobial, immunomodulatory preparations and other courses of these researches

Vishnevskiy I, Dobrovolskiy S., Zhitomir (Ukraine)
“Medherbs” represents celandine phyto-tea of Potopalsky A.
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2.2. Environmental sanitation

Dzyadevych S., Arkhypova V., Soldatkin A., El’skaya A., Martelet C., Jaffrezic-Renault N., Kyiv, Ecully Cedex (France)
Enzyme biosensor for tomatine detection in tomatoes
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Kovalenko P.G., Maliuta S.S., Kyiv
Effect of the elicitors on secondary metabolites production by licorice (Glycyrrhiza uralensis Fisch.) hairy roots cultures
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Drozda V., Kyiv
Integrated agricultural planting protection systems as a determining factor of the environmental sanitation
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Kocherga M., Drozda V., Kyiv
Biodiversity as an increasing factor of the adaptive potential and agrocenosis regulatory functions
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Lapa O., Drozda V., Kyiv
Highly specialized entomophags of the leaf-roller moth (Lepidoptera, Tortricidae), as a composite part of the apple-tree protection system
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Shevchenko T., Drozda V., Potopalsky A., Kyiv
The specificity of Trichogramma pintoi Voeg. (Hymenoptera, Trichogrammatidae) effect and productivity after native and modified nucleic acids use
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Shelestova V., Drozda V., Potopalsky A., Kyiv
The establishment of the rational growth methods of an Angoumois grain moth Sitotroga cerealella Oliv. (Lepidoptera, Gelechiidal) – a host-insect of the entomophages
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Appendixes:

Instruction on clinical study of preparation Amitozyn
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Conclusion on results of the limited clinical trials of Amitozyn preparation in the Institute of Oncology, Academy of Medical Sciences of Ukraine
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Manuals for the use of Izatizon preparation in veterinary
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Instruction for the clinical study of antivirus, antitumor, antimicrobial and immune correcting Izatizon preparation
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